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January 22, 2026
Shoulder

What causes shoulder pain? Common medical reasons and when to get checked

Andrew Chambler
Orthopaedic Surgeon

Shoulder pain can come from muscles, tendons, joints, or nerves — and the right treatment depends on identifying the true source.

Because many different conditions create similar symptoms, understanding the medical logic behind shoulder pain helps you know when simple care is enough and when expert assessment matters.

Why the Shoulder Is Prone to Pain

The shoulder is the most mobile joint in the human body. Unlike the hip, which trades movement for stability, the shoulder is designed for reach, rotation, lifting, and fine control. This freedom comes at a cost: the joint relies heavily on soft tissues — tendons, ligaments, labrum, and muscles — to stay stable. Any imbalance, strain, or degeneration in these structures can trigger pain.

Another reason shoulder pain is so common is overlap. Tendons, bursa, cartilage, and nerves sit in very tight anatomical spaces. When one structure becomes irritated, it can inflame its neighbors. This is why different disorders often feel similar at first — aching when lifting the arm, discomfort at night, or clicking during movement.

If you’re looking for a deeper clinical explanation of what causes shoulder pain, this orthopedic shoulder resource provides specialist-level context on assessment and treatment pathways.

Finally, shoulder pain doesn’t always originate in the shoulder itself. Neck nerve compression, posture-related muscle overload, or even referred pain from internal conditions can mimic local joint disease. That’s why correct diagnosis matters before treatment begins.

What Causes Shoulder Pain? The Most Common Medical Conditions

Several well-defined medical problems account for the majority of shoulder pain cases seen in clinics. Understanding their distinct mechanisms helps clarify why symptoms develop and how they should be addressed.

Rotator Cuff Tendon Injury

The rotator cuff is a group of four tendons that stabilize and rotate the shoulder. Overuse, degeneration, or sudden strain can inflame or tear these tendons. Pain typically appears when lifting the arm, reaching overhead, or lying on the affected side. In partial tears, weakness may be subtle. In full-thickness tears, raising the arm becomes difficult.

Shoulder Joint Arthritis

Arthritis develops when joint cartilage gradually wears down. In the shoulder, this produces deep aching pain, stiffness, and reduced range of motion. Unlike tendon problems, arthritis pain is often constant and worsens with general activity rather than specific movements.

Frozen Shoulder (Adhesive Capsulitis)

Frozen shoulder occurs when the joint capsule tightens and thickens, restricting movement. Pain often starts gradually and progresses to severe stiffness. Many patients struggle to lift or rotate the arm even passively. This condition is common after prolonged immobility, diabetes, or minor injuries.

Labral or Joint Stability Injury

The labrum is a rim of cartilage that deepens the shoulder socket. Tears or instability allow abnormal joint motion, leading to clicking, catching sensations, or sharp pain during certain movements. Athletes and individuals with repetitive overhead activity are more prone to this type of injury.

Within these core conditions, shoulder pain typically develops through three overlapping biological mechanisms:

  1. Inflammation of soft tissues from overuse or micro-trauma

  2. Mechanical instability or cartilage wear altering joint motion

  3. Nerve irritation from tight spaces or surrounding swelling


Practical early signs that often indicate a medically significant shoulder condition include:

  1. Pain when lifting or lowering the arm

  2. Night pain disrupting sleep

  3. Progressive stiffness or loss of motion

  4. Weakness during everyday tasks


From a diagnostic perspective, clinicians tend to separate shoulder pain into three functional patterns:

  1. Pain-dominant conditions driven by inflammation

  2. Stiffness-dominant conditions driven by capsular restriction

  3. Weakness-dominant conditions driven by tendon or muscle failure

Modern orthopedic literature supports these classifications. A detailed NCBI clinical overview of rotator cuff and shoulder disorders explains how these mechanisms guide imaging and treatment decisions in evidence-based practice.

How Doctors Identify the Real Cause

Because shoulder pain causes overlap, diagnosis follows a structured process rather than guesswork.

Clinical examination is the starting point. A physician evaluates posture, movement range, strength, joint stability, and pain response during specific tests. These maneuvers help distinguish tendon damage from joint stiffness or instability.

Imaging then refines the diagnosis. X-rays reveal arthritis or bone changes. Ultrasound visualizes tendon inflammation and tears in real time. MRI provides the most detailed view of soft tissue integrity, labral structure, and cartilage health. Imaging choices depend on examination findings rather than being ordered routinely.

This layered approach prevents mislabeling symptoms and ensures treatment targets the true pathology instead of only masking pain.

When Shoulder Pain Needs Specialist Assessment

Many mild shoulder strains improve with rest and basic care. However, certain situations warrant specialist evaluation.

Persistent pain lasting more than a few weeks, especially when accompanied by motion loss or weakness, suggests underlying structural injury. Sudden inability to lift the arm after trauma may indicate a tendon rupture. Night pain that doesn’t improve or progressive stiffness can signal frozen shoulder or joint degeneration.

Red-flag features include unexplained swelling, severe trauma, neurological symptoms radiating down the arm, or pain associated with systemic illness. These require medical assessment to rule out complex or non-musculoskeletal causes.

Treatment Options Based on the Cause

Treatment always follows diagnosis. For inflammatory or overuse conditions, physiotherapy, activity modification, and guided strengthening restore balanced mechanics. Anti-inflammatory strategies and targeted injections may reduce tissue irritation.

Frozen shoulder responds to supervised mobility therapy and gradual stretching programs. In resistant cases, controlled joint release procedures can restore motion.

Rotator cuff tears and unstable labral injuries sometimes require surgical repair when function is significantly impaired. Arthritis management ranges from rehabilitation and injections to joint replacement in advanced disease.

Matching treatment to pathology — not just symptoms — is the key principle behind long-term recovery.

Key Takeaways

Shoulder pain develops because the joint prioritizes mobility over structural stability. Rotator cuff disorders, arthritis, frozen shoulder, and labral injuries account for most cases, yet they can feel surprisingly similar at first. Careful clinical evaluation and targeted imaging clarify the diagnosis and guide appropriate treatment pathways.

Understanding shoulder pain empowers patients to seek timely assessment when symptoms persist, rather than relying on trial-and-error remedies. Early, accurate diagnosis remains the most reliable path to restoring comfortable, confident shoulder movement.

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